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AaviGen presents its novel heart-specific AAV capsids generated by its next-generation cardiac AAV platform

12/14/2022

Heidelberg, Germany – December 14, 2022 – For the first time, AaviGen presented data on its novel heart-specific adeno-associated viral (AAV) vector portfolio generated by its next- generation Cardiac AAV Platform (next-CAP) to an international audience. The invited presentation took place at the Cell & Gene Therapy Meeting (December 14 – 15, 2022) hosted by the Economic Partnership Initiative between Baden-Württemberg and United Kingdom. In addition, AaviGen showcased its dual-organ engineered AAV capsids suited, e.g., for neurological or muscular diseases with secondary involvement of the heart, such as Friedreich Ataxia or Muscular dystrophies. The meeting (https://cell-and-gene- therapy.b2match.io/home) is jointly organized by BIOPRO Baden-Württemberg, the UK Department for International Trade, Scottish Development International, Welsh Government, London & Partners and the cluster MedCity as well as the Northern Health Science Alliance.

“AaviGen‘s proprietary novel engineered AAV capsids are key to our comprehensive strategy to develop broadly applicable curative AAV-based gene therapies for rare and common heart diseases.” stated Dr. Martin Busch, COO of AaviGen. “The further expanding engineered AAV vector portfolio is the foundation to develop our therapeutic products and build partnerships in the rapidly growing field of DNA- and RNA-based treatments of cardiovascular and cardiopulmonary disorders” explicated Prof. Marc Lerchenmüller, AaviGen’s CFO. “We are extremely excited to see the growing results of our continued innovative work and the forward-looking investment made by Dietmar Hopp. 2023 will be a decisive part in AaviGen’s innovative journey.” said Prof. Patrick Most and Prof. Hugo Katus, CEO and CMO of AaviGen.

About AaviGen

AaviGen was founded in 2019 on the understanding that successful gene therapy requires optimized delivery of therapeutic targets to the diseased heart. AaviGen’s scientific approach is documented in numerous peer-reviewed scientific publications and validated by its founders’ track record in scientific innovations for the diagnosis and treatment of cardiac diseases, including gene therapy medicinal products. For more information, please see: www.aavigen.com

AaviGen Investor and Media Contact

Prof. Dr. Marc Lerchenmüller, Chief Financial Officer and Managing Director AaviGen, Heidelberg, Germany
T: +49 6221 568900
M: +49 151 51646589

marc.lerchenmueller@aavigen.com

AaviGen’s Forward-Looking Statements

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